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Progest-E Instructions

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If the weather is hot where you live, there is no need to worry about Progest E being affected by the heat during the shipping process. Progest E is very stable. Upon receipt, though it is not required, it is recommended to refrigerate the Progest E for the very best storage conditions, which will preserve its shelf life of 2 years. It is important to store Progest E out of direct light, which prevents product degradation. 

Our Progest E Oil is kept refrigerated at all times and sent out directly from the manufacturer. So you can be assured it is very fresh.

The resin used to make the bottle does not contain—BPAs, phthalates—or any other toxic chemicals listed for example under Proposition 65 in California or any other international toxics regulatory body.

If the bottle is too cold the drops won't be easy to measure, so estimate, or best let it warm up outside the refrigerator for 30 min or so. It is only necessary to refrigerate in hot or long term storage conditions.

The temperature of the solution when it is dispensed can make a difference, which is why we suggest removing it from the fridge (if you choose to refrigerate) about 30 minutes before use so it will be room temperature, and have consistency from day-to-day. The other factor is the amount of pressure applied - which can have a modest learning curve for individuals new to the product. If it is coming out in a stream, you are applying too much pressure to the bottle and doing so continuously. To get ‘drops’ try to use a quick pinch or squeeze and release action. There will still be a thin tail from the drop since oil has lower surface tension than water. 

It does not matter if drops are not perfect and vary time to time. It is not necessary to be exact.

Dr. Ray Peat's Progest E Oil Guidelines for Use:

You can determine the amount used based on your individual needs. If it's your first time trying this product, you might want to first put a few drops on your finger and then rub the Progest E on your gums and underneath the tongue. If your throat feels too sensitive, you can also mix the Progest E with olive oil or coconut oil and rub it into fleshy parts of your body for a topical application.

Men report using natural progesterone for stress, sleep, erectile dysfunction, and to protect against estrogen dominance as they age.

Specific usage directions will be sent by email once you have placed your order.

Progesterone is stored in the fat cells so not everyone will need the same amount or daily use. You must decide from your symptoms and individual need. It is best to rub it around your gums and let it absorb. A drop will look like the size of a drop that comes out of a dropper. It is easiest to measure the drop at room temperature. When PGE is cold, it will come out in a large drop, so estimate it, the amount does not have to be perfect.

Do not take progesterone while nursing. If pregnant do not use without consulting your doctor.

Natural bioidentical progesterone is an anti-tumor adaptogen and will stimulate your body to make it. There are no known toxic side-effects from natural progesterone. An overdose produces anesthesia. If you choose to discontinue PGE, it is recommended that you wean yourself off it and not stop abruptly. Stopping too fast or if still needed can cause side-effects. Some get hot flashes in three months and some the next day. Balancing the body chemistry is the key. Progesterone protects against the toxic effects of estrogen. By estrogen, meaning any kind, be it what your body makes, or what you take - natural or synthetic estrogens; or environmental estrogens, xeno-estrogens, herbal sources, such as black cohosh ("Remifemin"), sage and other herbal sources of estrogen.

If you have a goiter, progesterone's stimulation of thyroid secretion may lead to transient hyperthyroidism, so begin with smaller amounts cautiously. If so, it’s better to shrink the thyroid with thyroid glandular first, then progesterone will not cause this effect.

Women with cystic ovaries have reported spotting or sore breasts. If this happens with a small dose of progesterone, it can be a sign of cystic ovaries. Increasing the dosage of progesterone to 1/4 tsp. once and sometimes twice in one day can be enough to reverse this situation. Thyroid supplementation is usually necessary as well.

For general purposes, many people use Progest E Oil by rubbing a few drops on the lips and tongue, or rubbing it into the gums (it is good for the general health of the gums). These membranes are very thin, and the progesterone quickly enters the blood.

For the topical treatment of sun damaged skin, or acne, wrinkles, etc., the oil can be applied directly to the affected area. For topical treatment of arthritis, tendonitis, bursitis, or varicose veins, to speed absorption it is best to apply a few drops of olive oil (or jojoba or coconut oil) to the area, and then rub the Progest-E into and around the affected area. Some of the progesterone will be absorbed systemically, but the highest concentration is sustained in the local area, helping to correct the problem.

Please consult your health practitioner if you have further questions or need individualized guidance.

Why not use Natural Progesterone Cream?

Most progesterone creams contain less than 0.1% of progesterone, barely enough to be effective, except for mild female problems. Lab analysis of a cream called "Progest" shows that it contains less than 0.1% progesterone. Even true 3% progesterone creams are not enough for most women, which is why we recommend Dr. Peat's 10% progesterone dissolved in natural vitamin E. Most progesterone products are suspended in synthetic vitamin E or even worse, toxic oils, such as soybean or corn oils. Some have parabens and other toxic ingredients. Only dissolved progesterone is useable by the human body.

Warning: Progesterone and Wild Yam (Dioscorea) are not the same. Do not confuse progesterone with unaltered wild yam (dioscorea). The human body cannot convert wild yam to progesterone. The body makes progesterone only from cholesterol. The conversion of wild yam to natural progesterone must be done in a chemical factory. So all "progesterone" products labeled "wild yam" (underived) are bogus. Unaltered wild yam, in sufficient amounts, is toxic. Progesterone can be converted from other plants such as soy. 

Additional Information:

  • The size of the drops will vary depending on several factors for example, the amount of pressure applied squeezing the bottle, and the temperature of the solution (see additional information near the top of this doc).
  • A 60 mg drop contains 6 mg of progesterone and is a common minimum amount to use. An unpopped kernel of popcorn looks the same size as a 60 mg drop of Progest-E and can be used as a reference for people who don’t have a scale for weighing small drops. There are approximately 560 drops weighing 60 mg in each 34 ml bottle.  
  • See all products sold by Long Natural Health supporting women's health & hormonal support.

Dispensing and Storage Tips:

Prolonged exposure to higher temperatures and natural light is known to reduce the shelf life of natural vitamin E.  To get the greatest benefit from the natural vitamin E in Progest-E, store the product refrigerated, or in a cool dark place.

Natural vitamin E is more viscous when cold. To facilitate dispensing drops when storing refrigerated, use the following procedure: With the cap on, put your bottle of Progest-E upside down in a juice glass in the fridge. Remove the glass containing the bottle of Progest-E from the fridge approximately 20-30 minutes before use. This allows the solution to get to room temperature and makes dispensing drops easier. Storing the bottle upside down also ensures that the solution is always in the dropper tip ready for use.  

**The vitamin E in the Progest-E Complex is derived from soy, yet many people with soy allergies have no problem with Progest-E because often an allergic reaction is a response to soy proteins.

There are no proteins in the oily fractions of the plant (such as vitamin E), which is a highly purified distillate. If you have a soy allergy, it is best to first test on a small area of the skin (ex: ankle).

The progesterone in Dr. Peat’s Progest-E Complex is USP.

These statements are not recommendations or advice from Long Natural Health or Timothy Long. They are based on the teachings of Dr Ray Peat and Dr Lita Lee his student. LNH suggests you do your own research and consult your health care practitioner. 

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease. If you are pregnant or nursing, please consult your healthcare professional before using this or any product. Keep out of the reach of children.